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1.
JBRA Assist Reprod ; 23(2): 175-177, 2019 04 30.
Artigo em Inglês | MEDLINE | ID: mdl-30633473

RESUMO

Bowel endometriosis is a rare condition that may cause catastrophic complications necessitating immediate medical attention. This report describes the case of a patient diagnosed with endometriosis-induced bowel perforation. Albeit rare, bowel perforations caused by endometriosis should be considered in the differential diagnosis of women of reproductive age with abdominal pain.


Assuntos
Endometriose , Valva Ileocecal , Perfuração Intestinal , Abdome Agudo/etiologia , Feminino , Humanos , Valva Ileocecal/patologia , Valva Ileocecal/fisiopatologia , Pessoa de Meia-Idade
2.
Emerg Radiol ; 26(3): 277-282, 2019 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-30656481

RESUMO

OBJECTIVE: To study the association of a continent ileocecal valve and the degree of severity of the CT signs in patients presenting with large bowel obstruction due to colonic cancer. PATIENTS AND METHODS: Sixty-six patients undergoing emergency surgery for confirmed obstructive colonic cancer were included. The CT examinations were analyzed without consultation of the surgical results. For each patient, the diameter of the cecum at its widest point and that of the last ileal loop were measured. The ileocecal valve was considered incontinent when there was a distension of the last ileal loop greater than or equal to 25 mm. Below 25 mm, the ileocecal valve was considered continent. The presence of CT signs of severity of the LBO was noted, i.e., intestinal pneumatosis, absence of contrast enhancement of the large bowel wall, defect in the large bowel wall, and presence of extra-digestive air and ascites. RESULTS: Among the 66 patients included, 42 had an incontinent ileocecal valve and 24 had a continental ileocecal valve. There was a statistically significant difference between the two groups in the diametrical measurements of the cecum's widest point (mean diameter measured at 10.3 cm in patients with continent ileocecal valve vs 8.4 cm in patients with incontinent ileocecal valve, P = 0.0023). Patients with a continent valve had statistically higher rates of CT severity (79% vs 40%, P < 0.005). Perforation of the cecum remained rare (8%) and was only observed in patients with continent ileocecal valve in our series. CONCLUSION: Continence of the ileocecal valve appears to be statistically correlated both with cecum distension and the presence of CT signs of severity in patients with obstructive colonic cancer. As such, its presence must be retained as a risk factor for a pejorative evolution of this type of LBO and must be specified in the CT report of these patients.


Assuntos
Neoplasias do Colo/diagnóstico por imagem , Neoplasias do Colo/fisiopatologia , Valva Ileocecal/diagnóstico por imagem , Valva Ileocecal/fisiopatologia , Obstrução Intestinal/diagnóstico por imagem , Obstrução Intestinal/fisiopatologia , Tomografia Computadorizada por Raios X , Adulto , Idoso , Idoso de 80 Anos ou mais , Neoplasias do Colo/cirurgia , Meios de Contraste , Feminino , Humanos , Valva Ileocecal/cirurgia , Obstrução Intestinal/cirurgia , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Índice de Gravidade de Doença
3.
Surg Endosc ; 33(9): 2850-2857, 2019 09.
Artigo em Inglês | MEDLINE | ID: mdl-30426254

RESUMO

BACKGROUND: Right hemicolectomy is a very common surgery. Many studies compare different options for laparoscopic ileocolic anastomoses: intra- or extracorporeal; handsewn or stapled; side-to-side or end-to-side. However, there are no studies about the influence that peristalsis could have on this anastomosis. The aim of this study is to compare safety and feasibility of isoperistaltic and antiperistaltic anastomosis in terms of postoperative morbidity and mortality between both groups. The secondary endpoint is to compare long-term functional outcomes (chronic diarrhoea) and quality of life (GIQLI questionnaire) after a 1-year follow-up period. METHODS: A double-blind, randomised, prospective trial in patients undergoing scheduled surgery for right colon cancer with laparoscopic right hemicolectomy and isoperistaltic (ISO) or antiperistaltic (ANTI) ileocolic anastomoses. RESULTS: Hundred and eight patients were included in the study. Patients were randomised either to isoperistaltic or antiperistaltic configuration (54 ISO/ANTI). No significant differences in baseline variables were found. No differences in surgical time (130 [120-150] min ISO vs. 140 [127-160] ANTI, p = 0.481), nor in anastomotic time (19 [17-22] vs. 20 [16-25], p = 0.207) and nor in postoperative complications: 37.0% ISO versus 40.7% ANTI, (p = 0.693) were found. There were no differences in postoperative ileus (p = 0.112) nor in anastomotic leakage (3.7% vs. 5.56%, p = 1.00). Differences in "time to first flatus" and "time to first deposition" were found in favour of the antiperistaltic group (p = 0.004 and p = 0.017). Anastomotic configuration did not influence hospital stay (3 days [2-6] isoperistaltic vs. 3 [2-4] antiperistaltic, p = 0.236). During follow-up, there were no differences between the two groups at 1, 6 and 12 months (p = 0.154, p = 0.498 and p = 0.683), nor in chronic diarrhoea rates in GIQLI scores (24% ISO vs. 31.4% ANTI, p = 0.541). CONCLUSIONS: The isoperistaltic and antiperistaltic ileocolic anastomosis present similar results in terms of performance, safety and functionality. However, further studies must be carried out in order to assess relationship between postoperative ileus and anastomosis configuration. TRIAL REGISTRATION: Randomised Clinical trial (Identifier: NCT02309931).


Assuntos
Anastomose Cirúrgica , Fístula Anastomótica , Colectomia , Neoplasias do Colo/cirurgia , Íleus , Laparoscopia , Peristaltismo/fisiologia , Qualidade de Vida , Adulto , Anastomose Cirúrgica/efeitos adversos , Anastomose Cirúrgica/métodos , Fístula Anastomótica/etiologia , Fístula Anastomótica/fisiopatologia , Fístula Anastomótica/prevenção & controle , Fístula Anastomótica/psicologia , Colectomia/efeitos adversos , Colectomia/métodos , Método Duplo-Cego , Feminino , Humanos , Valva Ileocecal/fisiopatologia , Íleus/etiologia , Íleus/fisiopatologia , Íleus/prevenção & controle , Íleus/psicologia , Laparoscopia/efeitos adversos , Laparoscopia/métodos , Masculino , Pessoa de Meia-Idade , Resultado do Tratamento
4.
Neurogastroenterol Motil ; 31(2): e13492, 2019 02.
Artigo em Inglês | MEDLINE | ID: mdl-30353623

RESUMO

BACKGROUND: Linaclotide is efficacious in the management of irritable bowel syndrome with constipation (IBS-C), yet relatively little is known regarding its effect on human gastrointestinal physiology. The primary aim of the study was to examine the effect of linaclotide on change in pH across the ileocecal junction (ICJ), a proposed measure of cecal fermentation, and its relationship to symptoms and quality of life (QoL) in IBS-C. METHODS: A total of 13 participants with Rome III IBS-C underwent a standardized wireless motility capsule (WMC). Stool consistency was measured using the Bristol stool form scale (BSFS) and frequency with spontaneous bowel movements (SBM). Gastrointestinal symptoms and QoL were assessed using validated questionnaires. The WMC and questionnaires were repeated after 28 days of linaclotide 290 g po od. KEY RESULTS: Linaclotide reduced the change in pH across the ICJ (-2.4 ± 0.2 vs -2.1 ± 0.4, P = 0.01) as a function of a relative alkalinization of the cecum (5.2 ± 0.2 vs 5.5 ± 0.3, P = 0.02). Linaclotide accelerated colonic transit time (2650 minutes (2171-4038) vs. 1757 (112-3011), P = 0.02), increased colonic log motility index (15 ± 1.8 vs. 16.5 ± 1.8, P = 0.004) but had no effect of gastric emptying or small bowel transit. Change in pH across the ICJ correlated with improvement in symptom intensity, unpleasantness, and visceral sensitivity index (r = 0.62, P = 0.03, r = 0.63, P = 0.02, r = 0.62, P = 0.02) and with increases in BSFS type and SBM (r = 0.9, P < 0.0001, r = 0.6, P = 0.02). CONCLUSIONS & INFERENCES: Linaclotide's effects are confined to the colon where it increases cecal pH, potentially representing a reduction in cecal fermentation and accelerates colonic motility.


Assuntos
Ceco/efeitos dos fármacos , Agonistas da Guanilil Ciclase C/uso terapêutico , Concentração de Íons de Hidrogênio/efeitos dos fármacos , Síndrome do Intestino Irritável/tratamento farmacológico , Peptídeos/uso terapêutico , Adulto , Ceco/química , Ceco/fisiopatologia , Colo/efeitos dos fármacos , Constipação Intestinal/tratamento farmacológico , Feminino , Motilidade Gastrointestinal/efeitos dos fármacos , Trânsito Gastrointestinal/efeitos dos fármacos , Humanos , Valva Ileocecal/química , Valva Ileocecal/efeitos dos fármacos , Valva Ileocecal/fisiopatologia , Síndrome do Intestino Irritável/fisiopatologia , Masculino , Pessoa de Meia-Idade
6.
Dig Dis Sci ; 62(12): 3525-3535, 2017 12.
Artigo em Inglês | MEDLINE | ID: mdl-28871499

RESUMO

BACKGROUND: Small intestinal bacterial overgrowth (SIBO) is an increasingly recognized clinical syndrome; however, its etiophathogenesis is poorly understood. We hypothesized that loss of gastric acid, a delayed intestinal transit, and ileocecal valve dysfunction may contribute to the genesis of this syndrome. AIMS: Our primary aim was to assess these parameters using wireless motility capsule (WMC) testing and to correlate them with the presence or absence of SIBO. METHODS: We prospectively evaluated 30 consecutive patients at a tertiary care center with suspected SIBO, diagnosed by lactulose hydrogen breath testing (LBT), and small bowel aspirate microbiology. Patients underwent WMC testing to assess ileocecal junction pressure (ICJP), small bowel transit time (SBTT), and regional gastrointestinal pH. RESULTS: Thirty patients completed testing; 15 had a positive LBT, and 11 had a positive aspirate culture. As compared with LBT-negative patients, ICJP was lower (27.8 vs. 72.7 mmHg, p = 0.027), SBTT was longer (10.0 vs. 1.1 h, p = 0.004), gastric pH was higher (3.63 vs. 2.42, p < 0.01), and small bowel pH was higher (6.96 vs. 6.61, p = 0.05). A hypotensive ICJP (<46.61 mmHg) was more prevalent in LBT-positive patients as compared with LBT-negative patients (73.3 vs. 14.29%, p = 0.003). Logistic regression models were used to assess the magnitude of each measured WMC parameter and the presence of SIBO. p values ≤0.05 were considered statistically significant. CONCLUSIONS: Patients with SIBO have significantly lower ICJP, prolonged SBTT, and a higher gastrointestinal pH as compared to those without SIBO. These abnormalities may play different roles in the pathogenesis of SIBO, facilitating more targeted treatment to prevent recurrences of SIBO.


Assuntos
Síndrome da Alça Cega/etiologia , Disbiose/etiologia , Trânsito Gastrointestinal , Valva Ileocecal/fisiopatologia , Adulto , Feminino , Esvaziamento Gástrico , Humanos , Concentração de Íons de Hidrogênio , Masculino , Pessoa de Meia-Idade , Estudos Prospectivos
8.
Korean J Gastroenterol ; 62(6): 370-4, 2013 Dec.
Artigo em Coreano | MEDLINE | ID: mdl-24365737

RESUMO

Tuberculosis can occur anywhere in the gastrointestinal tract. However, anorectal tuberculosis has rarely been reported. A 46-years-old male presented with abdominal pain and perianal discharge of 30 years' duration. The patient had received operations for anal fistula and inflammation three times. Although he had been taking mesalazine for the past three years after being diagnosed with Crohn's disease, his symptoms persisted. Colonoscopy performed at our hospital revealed cicatricial change of ileocecal valve and diffuse ulcer scar with mild luminal narrowing of the ascending, transverse, and descending colon without active lesions. Multiple large irregular active ulcers were observed in the distal sigmoid and proximal rectum. An anal fistula opening with much yellowish discharge and background ulcer scar was observed in the anal canal. However, cobble-stone appearance and pseudopolyposis were not present. Therefore, we clinically diagnosed him as having intestinal tuberculosis with anal fistula and prescribed antituberculosis medications. Follow-up colonoscopy performed 3 months later showed much improved multiple large irregular ulcers in the distal sigmoid colon and proximal rectum along with completely resolved anal fistula without evidence of pus discharge.


Assuntos
Fístula/diagnóstico , Tuberculose Gastrointestinal/diagnóstico , Canal Anal , Anti-Inflamatórios não Esteroides/uso terapêutico , Antituberculosos/uso terapêutico , Colo/patologia , Colonoscopia , Doença de Crohn/diagnóstico , Doença de Crohn/tratamento farmacológico , Diagnóstico Diferencial , Fístula/patologia , Humanos , Valva Ileocecal/fisiopatologia , Masculino , Mesalamina/uso terapêutico , Pessoa de Meia-Idade , Proteína C/análise , Tuberculose Gastrointestinal/tratamento farmacológico
9.
Artigo em Coreano | WPRIM (Pacífico Ocidental) | ID: wpr-169071

RESUMO

Tuberculosis can occur anywhere in the gastrointestinal tract. However, anorectal tuberculosis has rarely been reported. A 46-years-old male presented with abdominal pain and perianal discharge of 30 years' duration. The patient had received operations for anal fistula and inflammation three times. Although he had been taking mesalazine for the past three years after being diagnosed with Crohn's disease, his symptoms persisted. Colonoscopy performed at our hospital revealed cicatricial change of ileocecal valve and diffuse ulcer scar with mild luminal narrowing of the ascending, transverse, and descending colon without active lesions. Multiple large irregular active ulcers were observed in the distal sigmoid and proximal rectum. An anal fistula opening with much yellowish discharge and background ulcer scar was observed in the anal canal. However, cobble-stone appearance and pseudopolyposis were not present. Therefore, we clinically diagnosed him as having intestinal tuberculosis with anal fistula and prescribed antituberculosis medications. Follow-up colonoscopy performed 3 months later showed much improved multiple large irregular ulcers in the distal sigmoid colon and proximal rectum along with completely resolved anal fistula without evidence of pus discharge.


Assuntos
Humanos , Masculino , Pessoa de Meia-Idade , Canal Anal , Anti-Inflamatórios não Esteroides/uso terapêutico , Antituberculosos/uso terapêutico , Colo/patologia , Colonoscopia , Doença de Crohn/diagnóstico , Diagnóstico Diferencial , Fístula/diagnóstico , Valva Ileocecal/fisiopatologia , Mesalamina/uso terapêutico , Proteína C/análise , Tuberculose Gastrointestinal/diagnóstico
10.
J Pediatr Surg ; 47(12): e43-6, 2012 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-23217916

RESUMO

Enterourachal fistulas are exceedingly rare in Crohn's patients. We report a case of a presumed enterourachal fistula that led to an infected urachal cyst. Preoperative medical treatment obliterated the fistula and avoided the need to resect bowel at the time of operation. We recommend consideration of this diagnosis in a Crohn's patient with a midline abdominal mass.


Assuntos
Doença de Crohn/complicações , Doença de Crohn/diagnóstico , Fístula Intestinal/complicações , Fístula Intestinal/diagnóstico , Cisto do Úraco/complicações , Cisto do Úraco/diagnóstico , Adolescente , Doença de Crohn/tratamento farmacológico , Endoscopia/métodos , Seguimentos , Humanos , Doenças do Íleo/complicações , Doenças do Íleo/diagnóstico , Doenças do Íleo/cirurgia , Valva Ileocecal/fisiopatologia , Fístula Intestinal/cirurgia , Masculino , Doenças Raras , Medição de Risco , Índice de Gravidade de Doença , Resultado do Tratamento , Cisto do Úraco/cirurgia
11.
World J Gastroenterol ; 18(46): 6801-8, 2012 Dec 14.
Artigo em Inglês | MEDLINE | ID: mdl-23239918

RESUMO

AIM: To explore whether patients with a defective ileocecal valve (ICV)/cecal distension reflex have small intestinal bacterial overgrowth. METHODS: Using a colonoscope, under conscious sedation, the ICV was intubated and the colonoscope was placed within the terminal ileum (TI). A manometry catheter with 4 pressure channels, spaced 1 cm apart, was passed through the biopsy channel of the colonoscope into the TI. The colonoscope was slowly withdrawn from the TI while the manometry catheter was advanced. The catheter was placed across the ICV so that at least one pressure port was within the TI, ICV and the cecum respectively. Pressures were continuously measured during air insufflation into the cecum, under direct endoscopic visualization, in 19 volunteers. Air was insufflated to a maximum of 40 mmHg to prevent barotrauma. All subjects underwent lactulose breath testing one month after the colonoscopy. The results of the breath tests were compared with the results of the pressures within the ICV during air insufflation. RESULTS: Nineteen subjects underwent colonoscopy with measurements of the ICV pressures after intubation of the ICV with a colonoscope. Initial baseline readings showed no statistical difference in the pressures of the TI and ICV, between subjects with positive lactulose breath tests and normal lactulose breath tests. The average peak ICV pressure during air insufflation into the cecum in subjects with normal lactulose breath tests was significantly higher than cecal pressures during air insufflation (49.33 ± 7.99 mmHg vs 16.40 ± 2.14 mmHg, P = 0.0011). The average percentage difference of the area under the pressure curve of the ICV from the cecum during air insufflations in subjects with normal lactulose breath tests was significantly higher (280.72% ± 43.29% vs 100% ± 0%, P = 0.0006). The average peak ICV pressure during air insufflation into the cecum in subjects with positive lactulose breath tests was not significantly different than cecal pressures during air insufflation 21.23 ± 3.52 mmHg vs 16.10 ± 3.39 mmHg. The average percentage difference of the area under the pressure curve of the ICV from the cecum during air insufflation was not significantly different 101.08% ± 7.96% vs 100% ± 0%. The total symptom score for subjects with normal lactulose breath tests and subjects with positive lactulose breath tests was not statistically different (13.30 ± 4.09 vs 24.14 ± 6.58). The ICV peak pressures during air insufflations were significantly higher in subjects with normal lactulose breath tests than in subjects with positive lactulose breath tests (P = 0.005). The average percent difference of the area under the pressure curve in the ICV from cecum was significantly higher in subjects with normal lactulose breath tests than in subjects with positive lactulose breath tests (P = 0.0012). Individuals with positive lactulose breath tests demonstrated symptom scores which were significantly higher for the following symptoms: not able to finish normal sized meal, feeling excessively full after meals, loss of appetite and bloating. CONCLUSION: Compared to normal, subjects with a positive lactulose breath test have a defective ICV cecal distension reflex. These subjects also more commonly have higher symptom scores.


Assuntos
Valva Ileocecal/fisiopatologia , Intestino Delgado/microbiologia , Adulto , Idoso , Infecções Bacterianas/diagnóstico , Testes Respiratórios , Ceco/fisiopatologia , Colonoscopia , Feminino , Humanos , Íleo/fisiopatologia , Insuflação , Lactulose/metabolismo , Masculino , Pessoa de Meia-Idade , Projetos Piloto
12.
Arq Gastroenterol ; 45(3): 212-8, 2008.
Artigo em Inglês | MEDLINE | ID: mdl-18852949

RESUMO

BACKGROUND: The observation of cecoileal reflux to barium enema is not rare; however, its causes and consequences have not been widely investigated. Considering that ileocecal junction exerts a function as barrier to invasion of bacteria from colon to small bowel, it seems interesting to study the intestinal microflora in subjects carrying cecoileal reflux. AIMS: This study aims at evaluating the ileal flora in individuals with cecoileal reflux. METHODS: A group of 36 subjects comprising 30 females and 6 males with a mean age of 54 years was assessed. Twenty-five individuals with cecoileal reflux and 11 without cecoileal reflux were submitted to small intestine contamination evaluation through the breath test with lactulose-H2 and measurement of the orocecal transit time by means of alternate current biosusceptometry. Small intestine bacterial overgrowth was characterized by orocecal transit time-H2 shortening. RESULTS: Comparison of basal H2, orocecal transit time-H2 and orocecal transit time-alternate current biosusceptometry measurements did not statistically differ between the groups with and without cecoileal reflux. Orocecal transit time-H2 was significantly smaller than orocecal transit time-alternate current biosusceptometry, particularly in individuals with cecoileal reflux. A significant correlation between the two methods was observed only in relation to control, not existing in relation to cecoileal reflux group. CONCLUSIONS: Smaller orocecal transit time-H2 and the loss of correlation with orocecal transit time-alternate current biosusceptometry observed in the individuals with cecoileal reflux suggest a differentiated behavior for such group relative to control, which could be associated with small intestine bacterial overgrowth.


Assuntos
Bactérias/crescimento & desenvolvimento , Trânsito Gastrointestinal/fisiologia , Intestino Delgado/microbiologia , Adulto , Idoso , Testes Respiratórios/métodos , Estudos de Casos e Controles , Feminino , Humanos , Valva Ileocecal/microbiologia , Valva Ileocecal/fisiopatologia , Intestino Delgado/fisiopatologia , Masculino , Pessoa de Meia-Idade , Adulto Jovem
13.
Arq. gastroenterol ; 45(3): 212-218, jul.-set. 2008. ilus, tab
Artigo em Inglês | LILACS | ID: lil-494329

RESUMO

BACKGROUND: The observation of cecoileal reflux to barium enema is not rare; however, its causes and consequences have not been widely investigated. Considering that ileocecal junction exerts a function as barrier to invasion of bacteria from colon to small bowel, it seems interesting to study the intestinal microflora in subjects carrying cecoileal reflux. AIMS: This study aims at evaluating the ileal flora in individuals with cecoileal reflux. METHODS: A group of 36 subjects comprising 30 females and 6 males with a mean age of 54 years was assessed. Twenty-five individuals with cecoileal reflux and 11 without cecoileal reflux were submitted to small intestine contamination evaluation through the breath test with lactulose-H2 and measurement of the orocecal transit time by means of alternate current biosusceptometry. Small intestine bacterial overgrowth was characterized by orocecal transit time-H2 shortening. RESULTS: Comparison of basal H2, orocecal transit time-H2 and orocecal transit time-alternate current biosusceptometry measurements did not statistically differ between the groups with and without cecoileal reflux. Orocecal transit time-H2 was significantly smaller than orocecal transit time-alternate current biosusceptometry, particularly in individuals with cecoileal reflux. A significant correlation between the two methods was observed only in relation to control, not existing in relation to cecoileal reflux group. CONCLUSIONS: Smaller orocecal transit time-H2 and the loss of correlation with orocecal transit time-alternate current biosusceptometry observed in the individuals with cecoileal reflux suggest a differentiated behavior for such group relative to control, which could be associated with small intestine bacterial overgrowth.


RACIONAL: Fato de observação não rara, é o encontro de refluxo cecoileal durante realização de enema opaco. As causas e conseqüências deste achado têm sido pouco estudadas. OBJETIVOS: Sabendo que a junção ileocecal exerce função de barreira e proteção contra a invasão do delgado pela flora colônica, realizou-se o presente estudo com a finalidade de investigar se existe contaminação ileal em indivíduos com refluxo cecoileal ao enema opaco. MÉTODOS: Investigaram-se 36 indivíduos, 30 mulheres e 6 homens, idade média de 54 anos, 25 com e 11 com ausência refluxo cecoileal. Todos submetidos a pesquisa de contaminação bacteriana do delgado por intermédio de teste respiratório com lactulose-H2 e a determinação do tempo de trânsito orocecal por meio de biossusceptometria de corrente alternada. A caracterização da contaminação do delgado foi baseada no encurtamento do tempo de trânsito orocecal medido pelo teste da lactulose-H2. RESULTADOS: A comparação dos valores basais do H2, do tempo de trânsito orocecal-H2 e tempo de trânsito orocecal-biossusceptometria de corrente alternada não diferiram estatisticamente entre os grupos com e sem refluxo cecoileal. Quando comparados os tempo de trânsito orocecal-H2 e tempo de trânsito orocecal-biossusceptometria, foi observado aumento de tendência de redução do primeiro em relação ao último nos grupos com refluxo cecoileal e correlação significante entre os dois métodos apenas no grupo-controle, inexistindo nos com refluxo cecoileal. CONCLUSÃO: Encurtamento do tempo de trânsito orocecal-H2 e sua perda de correlação com o tempo de trânsito orocecal-biossusceptometria observado em indivíduos com refluxo cecoileal, sugerem comportamento diferenciado deste grupo em relação ao grupo-controle. Possível explicação para as diferenças registradas entre os grupos, seria a presença de flora anômala nos indivíduos com refluxo cecoileal.


Assuntos
Adulto , Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Adulto Jovem , Bactérias/crescimento & desenvolvimento , Trânsito Gastrointestinal/fisiologia , Intestino Delgado/microbiologia , Testes Respiratórios/métodos , Estudos de Casos e Controles , Valva Ileocecal/microbiologia , Valva Ileocecal/fisiopatologia , Intestino Delgado/fisiopatologia , Adulto Jovem
14.
Ter Arkh ; 75(4): 44-6, 2003.
Artigo em Russo | MEDLINE | ID: mdl-12793137

RESUMO

AIM: To study prevalence of markers of connective tissue dysplasia (CTD) in patients with primary insufficiency of ileocecal valve (PIIV). MATERIAL AND METHODS: The trial included 87 patients (21 men and 66 women aged 13 to 64 years) with irrigoscopy-documented barium reflux into the small intestine. The occurrence of external phenotypical markers of CTD was studied at general examination and antropometry, of visceral ones--at ultrasound investigation of the heart, abdominal organs and the kidneys. The state of the connective tissue was assessed by skin biopsy histology. RESULTS: PIIV patients demonstrated a great number of dysembryogenic stigma typical for CTD: asthenic constitution, hypotrophy, chest deformation, foot and spine ligaments weakness, etc. A radial-lacunar type of the iris of the eye was described for the first times among external CTD phenotypical markers. Such visceral CTD markers as mitral prolapse, left ventricular false chorda, gallbladder deformity, nephroptosis occurred in the PIIV patients significantly more frequently. Morphological characteristics of the skin in PIIV patients were similar to those registered in patients with cardial manifestations of CTD. CONCLUSION: The above external and visceral phenotypical markers and skin morphology give arguments for referring PIIV to signs of CTD. Such position can open new prospects for pathogenetic treatment of PIIV.


Assuntos
Doenças do Tecido Conjuntivo/fisiopatologia , Valva Ileocecal/fisiopatologia , Vísceras/fisiopatologia , Adolescente , Adulto , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Fenótipo
15.
Med. mil ; 59(1): 33-34, ene.-mar. 2003. ilus
Artigo em Es | IBECS | ID: ibc-37492

RESUMO

Presentamos el caso de una mujer de 86 años con episodios de dolor abdominal etiquetados de cuadros de suboclusión intestinal y anemia ferropénica de varios meses de evolución. Acude a Urgencias por empeoramiento del dolor cólico y deposiciones diarreicas. En la exploración abdominal se aprecia una masa epi-mesogástrica en forma de "barra gruesa". Comentamos la rareza de la invaginación intestinal en el adulto que apenas supone el 10 por ciento de las causas de obstrucción intestinal y la dificultad de conseguir un adecuado diagnóstico preoperatorio. Describimos los hallazgos clínicos y radiológicos, haciendo hincapié en la importancia de las técnicas exploratorias en la aproximación diagnóstica. Ecografia, TAC y RNM abdominal pueden ofrecer unos magníficos resultados (AU)


Assuntos
Idoso , Feminino , Humanos , Obstrução Intestinal/etiologia , Intussuscepção/complicações , Valva Ileocecal/fisiopatologia , Abdome Agudo/etiologia , Intussuscepção/diagnóstico , Anemia Ferropriva/complicações
16.
Asian J Surg ; 25(3): 220-5, 2002 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-12376219

RESUMO

OBJECTIVES: We previously reported clinicopathological data on 78 patients who underwent a right hemicolectomy from 1990 to 1997. Our results indicated that the ileocaecal valve [ICV] and lymphoid tissue of the terminal ileum might, together, play a protective and local immune role against carcinoma invasion. Furthermore, we previously reported that mucin histochemical features of the transitional zone [TZ] might also play a role in predicting metastasis and, thus, prognosis. The aim of this study was to examine the clinicopathological correlation between lymphoid infiltration and mucin secretion in the terminal ileum with carcinoma of the right colon. METHODS: According to the proximity of the tumour to the ICV, a total of 16 specimens with lymphoid infiltration to and around [< 1 cm] the ICV were studied in order to identify the mucin expression and histochemical features of the TZ as a prognostic indicator. RESULTS: Patients with sulphomucin-staining tumours in the terminal ileum and ICV had a relatively favourable course. Even when the clinical staging was the same for different tumours, greater lymphoid infiltration in the ICV, greater staining for sulphomucin in the ICV and a relatively favourable course were observed in nine patients. The sulphomucin-type TZ showed a favourable course as well. On the other hand, patients with sialomucin staining of the ICV and the TZ tended to have low-grade lymphoid infiltration and a very poor course, although two patients with moderately high-grade lymphoid infiltration had a favourable course. Overall survival was significantly associated with the mucin type of the ICV [p < 0.01]. CONCLUSIONS: Our results indicated that lymphoid infiltration of the terminal ileum may lead to an alteration in mucin secretion and, thus, play a protective role in the invasive and metastatic process of advanced right colon carcinoma.


Assuntos
Carcinoma/metabolismo , Carcinoma/patologia , Neoplasias do Colo/metabolismo , Neoplasias do Colo/patologia , Valva Ileocecal/metabolismo , Valva Ileocecal/patologia , Íleo/metabolismo , Íleo/patologia , Tecido Linfoide/metabolismo , Tecido Linfoide/patologia , Mucinas/metabolismo , Mucinas/fisiologia , Idoso , Idoso de 80 Anos ou mais , Carcinoma/fisiopatologia , Neoplasias do Colo/fisiopatologia , Feminino , Humanos , Valva Ileocecal/fisiopatologia , Íleo/fisiopatologia , Tecido Linfoide/fisiopatologia , Masculino , Pessoa de Meia-Idade , Invasividade Neoplásica
17.
Klin Med (Mosk) ; 80(3): 37-40, 2002.
Artigo em Russo | MEDLINE | ID: mdl-11980157

RESUMO

Combination of bronchial asthma (BA) with Bauhin's valve failure (BVF) is characterized by exogenic form of BA, extrapulmonary allergy, digestion problems. Examination of 36 such patients using endoscopy, manometry and tube duodenography has shown frequent chronic disorder of duodenal patency and gastroesophageal reflux, dysbacteriosis of the large and small intestines. High concentration of middle mass molecular peptides reflects endogenic intoxication associated with abnormal composition of intestinal microflora. The above alterations give grounds to consider BVF as a factor of BA pathogenesis.


Assuntos
Asma/fisiopatologia , Obstrução Duodenal/fisiopatologia , Valva Ileocecal/fisiopatologia , Adolescente , Adulto , Idoso , Asma/complicações , Asma/diagnóstico , Obstrução Duodenal/complicações , Obstrução Duodenal/diagnóstico , Feminino , Humanos , Masculino , Pessoa de Meia-Idade
18.
Clin Transplant ; 13(5): 389-94, 1999 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-10515219

RESUMO

Preservation of the ileocecal valve improves absorptive function and decreases the amount of small bowel needed for survival in patients with short gut syndrome. We compared the results of small and large bowel transplant (SLBTx), small bowel transplant only (SBTx), and SBTx with the ileocecal valve (ICVTx) in a porcine model. Total enterectomy was performed on 18 Yorkshire-Landrace pigs followed by orthotopic SBLTx (n = 6), SBTx (n = 6), and ICVTx (n = 6). A jejunostomy and an ileostomy were constructed for biopsies. Overall mean survival was 17 d with no statistically significant difference between groups. Rejection was seen in 6/6 SLBTx, 4/6 SBTx, and 4/6 ICVTx recipients. Acute rejection was seen in 84.3% of SLBTx, 52.3% of SBTx, and 42.5% of the ICVTx mucosal biopsy samples. Two cases of intra-abdominal infection were in the ICVTx group only. Weight loss was 147 g/d in the SLBTx group, 643 g/d in the SBTx group, and 393 g/d in the ICVTx group. While the functional outcome after SLBTx and ICVTx was noticeably better than the SBTx group, the increased rejection and intra-abdominal infection rates make transplanting the large bowel or the ileocecal valve a less attractive clinical option.


Assuntos
Rejeição de Enxerto , Valva Ileocecal/transplante , Intestino Grosso/transplante , Intestino Delgado/transplante , Doença Aguda , Animais , Doença Enxerto-Hospedeiro/etiologia , Valva Ileocecal/fisiopatologia , Infecções/etiologia , Intestino Grosso/fisiopatologia , Intestino Delgado/fisiopatologia , Complicações Pós-Operatórias , Suínos , Redução de Peso
19.
Arch. boliv. med ; 4(53/54): 63-4, 1997. ilus
Artigo em Espanhol | LILACS | ID: lil-216621

RESUMO

Vólvulo de ciego término no muy correcto desde el punto de vista anatómico. Halvosen y Se (1975) en su revisión de 30 casos señalan que están involucrados el ileón terminal y cólon ascendente, entonces el término más propiado seria el vólvulo ileocecal. El vólvulo por lo común ocurre en sentido horario; el giiigante varía de 90 grados hasta 3 giros completos, el vólvulo depende de movilidad anormal del ciego y cólon ascendente. Esto pude tomar la forma de una mala rotación completa, un mecenterio ilececal común, o una fijación imperfecta


Assuntos
Humanos , Obstrução Intestinal/diagnóstico , Obstrução Intestinal/terapia , Valva Ileocecal/fisiologia , Valva Ileocecal/fisiopatologia , Valva Ileocecal/patologia
20.
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